Saturday, December 1, 2012

Treatment of SLE

First line treatment:


Hydroxychloroquine

Mild SLE: low dose steroid
Aggressive SLE: moderate dose steroid
Severe SLE: high dose steroid, combine with either cyclophosphamide, mycophenolate mofetil, or azathioprine


Hydroxychloroquine: continue indefinitely

Switch from cyclophosphamide to mycophenolate mofetil, or azathioprine in 3 to 6 mo