Saturday, November 1, 2008

IBD

IBD: diarrhea, bleeding, fever, weight loss, abdominal pain, Dx: endoscopy
CD: palpable pain, skipping lesions, kidney stone, gallstone, vitB12, calcium, iron, vit K deficiency, ASCA antibody,
UC: confine to large bowel, No mouth or anal involvment, No fistula, No skip lesions, more bleeding, ANCA,

Txt: mesalamine , or sulfasalazine, acute exacerbation using steroid
CD: pentasa
UC: Asacol
rowasa for rectal disease

azathioprine and 6-mercaptopurine to substitue steroid
anal CD: ciprofoxacin and metronidazole
CD with fistula: infliximab, do PPD first

Surgery: curative for UC, not used for CD

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